Presentation: Towards a High-Pressure Structural Biology Instrumention Suite at CHESS

Presentation: Towards a High-Pressure Structural Biology Instrumention Suite at CHESS

Conclusions

  • Pressure directly affects the structure, and therefore is it essential to decipher the structure using high-pressure SAXS and crystallography, to investigate the energy landscape of proteins and enzymes.
  • CHESS provides a demonstrated capability to perform high-pressure SAXS and crystallography (and FTIR), that is unique in the United States.
  • In concert with users and collaborators, this high pressure biological research capability opens access to a profoundly important, yet mostly unexplored biological questions.