Our Game-Changing Pressure Cycling Technology ("PCT")

Pressure BioSciences, Inc. is a life sciences tools company focused on the development, marketing, and sale of proprietary laboratory instrumentation and associated consumables based on our game-changing Pressure Cycling Technology ("PCT").

A Patented, Enabling Technology Platform

PCT is a patented, enabling technology platform that uses alternating cycles of hydrostatic pressure between ambient and ultra-high levels (up to 90,000 psi) to safely, conveniently and reproducibly control the actions of molecules in biological samples, e.g., the rupture (lysis) of cells and tissues from human, animal, plant and microbial sources, and the inactivation of pathogens.

Addressing the Challenging Problems Inherent in Biological Sample Preparation

We currently focus the majority of our efforts on the development and sale of PCT-enhanced systems (instruments and consumables) to address the challenging problems inherent in biological sample preparation, a crucial laboratory step performed by tens of thousands of scientists worldwide working in biological life sciences research.

Through 2015, we have nearly 300 PCT Systems installed in over 150 leading academic, government, biotech and pharma laboratories worldwide, with primary applications in biomarker discovery, forensics, agriculture and pathology.

Advantages of the PCT Platform

There are over 100 scientific papers published on the advantages of the PCT platform, many by key opinion leaders worldwide. Such advantages include:

  • Extraction and recovery of more membrane proteins
  • Enhanced protein digestion
  • Differential lysis in a mixed sample base
  • Pathogen inactivation
  • Increased DNA detection
  • Exquisite sample preparation process control

Strategic Alliances

On January 12, 2016, SCIEX, a global leader in life science analytical technologies, announced an exclusive co-marketing agreement with PBI. This relationship will uniquely position SCIEX to address a major challenge in complex sample preparation by marketing a complete solution to increase the depth, breadth, and reproducibility of protein extraction, digestion and quantitation in all tissue types, including challenging samples like tumors. This focus on improved sample preparation will enable scientists to extract more proteins reproducibly from complex sample types, potentially yielding superior biological insights and discoveries.