Ping Jiang^a Fumin Li^b Jie Ding^a

^aPPD, 8551 Research Way, Middleton, WI 53562

^bPPD, 3230 Deming Way, Middleton, WI 53562

Louise Bundgaard, Simonas Savickas, and Ulrich auf dem Keller

Department of Biotechnology and BiomedicineTechnical University of Denmark, Kongens Lyngby, Denmark

Chan Hyun Na1,2,3,4, ǂ , Neeraj Sharma1, ǂ , Anil K. Madugundu1,7,8, Ruiqiang Chen1,2, Melis Atalar Aksit1 , Gedge D. Rosson9 , Garry R. Cutting1 ,* and Akhilesh Pandey1,2,5,6, *

1 McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA 2 Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA 3 Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA 4 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA 5 Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA 6 Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA 7 Institute of Bioinformatics, Bangalore, India 8 Manipal Academy of Higher Education (MAHE), Manipal 576104, Karnataka, India 9 Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

Yujia He^a1Abidali Mohamedali^b1Canhua Huang^a Mark S.Baker^c Edouard C.Nice^acd

^aWest China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, PR China

^bDepartment of Molecular Sciences, Faculty of Science and Engineering, Macquarie University, New South Wales 2109, Australia

^cDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, New South Wales 2109, Australia

^dDepartment of Biochemistry and Molecular Biology, Monash University, Clayton, Australia

Wolfgang Faigle,¹Carolina Cruciani,¹Witold Wolski,²Bernd Roschitzki,²Marco Puthenparampil,¹Paula Tomas-Ojer,¹Carla Sellés-Moreno,¹Thomas Zeis,³Ivan Jelcic,¹Nicole Schaeren-Wiemers,³Mireia Sospedra,^1,†and Roland Martin^1,*†