Improved Protein Recovery from Rat Pancreas Tissue Using Pressure Cycling Technology (PCT) and the ProteoSolve-SB Kit

Improved Protein Recovery from Rat Pancreas Tissue Using Pressure Cycling Technology (PCT) and the ProteoSolve-SB Kit

Introduction
Pancreatic cancer has a very high mortality rate, primarily due to the fact that it is usually diagnosed at an advanced stage (Ranganathan 2009). Early diagnosis of this devastating disease could be crucial for improving treatment options and survival rates. The pancreas, as the site of insulin secretion, is also intimately linked to diabetes. A better understanding of the normal and diseased pancreatic proteome might give researchers better insights into pancreatic function and development in health and dysfunction in various disease states (Tonack et al., 2009; Chen et al., 2007).